Naive B cell

A naive B cell is a type of B cell[1][2] that has not been exposed to antigen.

B-cell chronic lymphocytic leukemia cells are produced from naive B cells.

References

  1. ^ Airoldi I, Raffaghello L, Cocco C, et al. (January 2004). "Heterogeneous expression of interleukin-18 and its receptor in B-cell lymphoproliferative disorders deriving from naive, germinal center, and memory B lymphocytes". Clin. Cancer Res. 10 (1 Pt 1): 144–54. doi:10.1158/1078-0432.CCR-1026-3. PMID 14734463. http://clincancerres.aacrjournals.org/cgi/pmidlookup?view=long&pmid=14734463. 
  2. ^ Feldhahn N, Schwering I, Lee S, et al. (November 2002). "Silencing of B cell receptor signals in human naive B cells". J. Exp. Med. 196 (10): 1291–305. doi:10.1084/jem.20020881. PMC 2193982. PMID 12438421. http://www.jem.org/cgi/pmidlookup?view=long&pmid=12438421. 
Lymphoid/
HSC:CFU-L
Plasma · Memory · Follicular · Marginal-zone · Naive · Pre-B
Lymphopoiesis

M: LMC

cell/phys/auag/auab/comp, igrc

imdf/ipig/hyps/tumr

proc, drug(L3/4)